Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609605 | 1.00 | TRPC6 (0.52) | TRPC6SMN1; SMN2KDM4EGLAHTT | |
| SCHEMBL27676281 | 0.94 | TRPC6 (0.48) | TRPC6SMN1; SMN2KDM4EGLAHTT | |
| SCHEMBL611802 | 0.91 | TRPC6 (0.47) | TRPC6SMN1; SMN2KDM4EGLAHTT | |
| SCHEMBL608705 | 0.87 | QDPR (0.55) | TRPC6TNKSQDPR | |
| SCHEMBL159379 | 0.84 | GABRP (0.43) | TRPC6SMN1; SMN2KDM4EGLAHTT | |
| SCHEMBL28143370 | 0.84 | KDM4E (0.44) | TRPC6SMN1; SMN2KDM4EGLAHTT | |
| SCHEMBL27926722 | 0.83 | TRPC6 (0.51) | TRPC6TNKSEGLN1 | |
| SCHEMBL265000 | 0.82 | SLC18A3 (0.51) | SMN1; SMN2QDPRKCNH2BACE1NAMPT | |
| SCHEMBL10179413 | 0.82 | KDM4E (0.68) | TRPC6SMN1; SMN2KDM4EGLAHTT | |
| SCHEMBL21045776 | 0.80 | TRPC6 (0.54) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222636-A | Deuterated compounds as CDK4/6 inhibitors | 甘李药业股份有限公司 | 2023-12-12 | — | — | CN | disclosed |