Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TNKS | O95271 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784355 | 0.82 | PIM1 (0.50) | HPGDMAPK1NPSR1KMT2ATNKS | |
| SCHEMBL30783824 | 0.82 | TNKS (0.42) | HPGDMAPK1NPSR1KMT2ATNKS | |
| SCHEMBL30784435 | 0.80 | PIK3CA (0.46) | HSD17B10AKT1ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL30784371 | 0.79 | PRKDC (0.38) | HPGDMAPK1NPSR1KMT2ATNKS | |
| SCHEMBL4985818 | 0.74 | SMN1; SMN2 (0.44) | HPGDMAPK1NPSR1KMT2ATNKS | |
| SCHEMBL30783864 | 0.73 | KMT2A (0.44) | HPGDMAPK1NPSR1KMT2AMEN1 | |
| SCHEMBL27167464 | 0.72 | SMN1; SMN2 (0.55) | HPGDKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL30054892 | 0.72 | SMN1; SMN2 (0.55) | HPGDKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL30784542 | 0.72 | HTR3A (0.43) | HPGDMAPK1NPSR1KMT2AMEN1 | |
| SCHEMBL4981345 | 0.66 | TSHR (0.45) | HPGDMAPK1NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |