Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 4/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784415 | 0.80 | PIK3CB (0.40) | PRKDCELANEMGLLAPAF1CDC25B | |
| SCHEMBL30784253 | 0.79 | HPGD (0.43) | PRKDCTNKSTNKS2HPGDMAPK1 | |
| SCHEMBL30783645 | 0.79 | APAF1 (0.37) | PRKDCELANEHPGDMAPK1NPSR1 | |
| SCHEMBL30784435 | 0.74 | PIK3CA (0.46) | PRKDCCDC25BHSD17B10 | |
| SCHEMBL30784355 | 0.73 | PIM1 (0.50) | TNKSTNKS2HPGDMAPK1NPSR1 | |
| SCHEMBL30783824 | 0.70 | TNKS (0.42) | TNKSTNKS2HPGDMAPK1NPSR1 | |
| SCHEMBL4985818 | 0.66 | SMN1; SMN2 (0.44) | TNKSTNKS2HPGDMAPK1NPSR1 | |
| SCHEMBL2420509 | 0.64 | HTR3A (0.70) | ELANEMGLLAPAF1CDC25BCASP3 | |
| SCHEMBL30054892 | 0.64 | SMN1; SMN2 (0.55) | HPGDMEN1TSHRKMT2AHSD17B10 | |
| SCHEMBL27167464 | 0.64 | SMN1; SMN2 (0.55) | HPGDMEN1TSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |