Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 5/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783824 | 0.83 | TNKS (0.42) | PIM1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL30784253 | 0.82 | HPGD (0.43) | PIM1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL4985818 | 0.78 | SMN1; SMN2 (0.44) | PIM1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL30054892 | 0.76 | SMN1; SMN2 (0.55) | KMT2AMEN1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL27167464 | 0.76 | SMN1; SMN2 (0.55) | KMT2AMEN1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL30784371 | 0.73 | PRKDC (0.38) | KMT2AMEN1TSHRHSD17B10TNKS | |
| SCHEMBL30783861 | 0.72 | KMT2A (0.48) | PIM1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL29295193 | 0.71 | NLRP3 (0.44) | KMT2AMEN1TSHRHSD17B10TNKS | |
| SCHEMBL30784436 | 0.70 | PIM1 (0.47) | PIM1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL30784070 | 0.70 | HTR3A (0.47) | PIM1KMT2AMEN1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |