Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269580 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBGAAUSP2TP53 | |
| SCHEMBL2744891 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBGAAUSP2TP53 | |
| SCHEMBL10489884 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBGAAUSP2TP53 | |
| SCHEMBL2998004 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBGAAUSP2TP53 | |
| SCHEMBL30872885 | 0.76 | SLC6A3 (0.53) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL14240305 | 0.75 | ALDH1A1 (0.52) | SMN1; SMN2POLBHDAC8KDM4EALDH1A1 | |
| SCHEMBL3263369 | 0.74 | HTT (0.54) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| Pyrrole SCHEMBL1260091 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBGAAUSP2TP53 | |
| SCHEMBL13959836 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBGAAUSP2TP53 | |
| SCHEMBL3170737 | 0.73 | ABL1 (0.55) | SMN1; SMN2TP53HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |