Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175236 | 0.78 | DRD2 (0.46) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL19027921 | 0.77 | CA1 (0.44) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL29175237 | 0.76 | MEN1 (0.42) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL13712849 | 0.75 | TDP1 (0.54) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL19027494 | 0.72 | CA1 (0.46) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL22759722 | 0.72 | CPB2 (0.41) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL29357820 | 0.72 | TDP1 (0.44) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL19027486 | 0.72 | DRD2 (0.45) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL31079918 | 0.71 | TDP1 (0.47) | TDP1GAAMEN1KMT2ADRD2 | |
| SCHEMBL25381100 | 0.71 | CAMK2D (0.48) | TDP1GAAMEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486888-A | Tricyclic compounds and uses thereof | 和记黄埔医药（上海）有限公司 | 2024-02-02 | — | — | CN | disclosed |