Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22759722 | 0.87 | CPB2 (0.41) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL30786394 | 0.76 | TDP1 (0.44) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL29357820 | 0.73 | TDP1 (0.44) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL25381100 | 0.72 | CAMK2D (0.48) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL21069375 | 0.71 | STK17B (0.44) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL22442538 | 0.71 | MEN1 (0.41) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL22442540 | 0.71 | MEN1 (0.41) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL31082349 | 0.71 | DRD2 (0.42) | TDP1DRD2CA1CA2CA12 | |
| SCHEMBL28699281 | 0.71 | CAMK2D (0.45) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL25344478 | 0.70 | DYRK1A (0.40) | TDP1DRD2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486888-A | Tricyclic compounds and uses thereof | 和记黄埔医药（上海）有限公司 | 2024-02-02 | — | — | CN | disclosed |