SCHEMBL3078752

SCHEMBL3078752

Cc1ccccc1N[C@@H](C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
HPGD P15428 5/20 0.50
ALDH1A1 P00352 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 2/20 0.48
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
PGR P06401 1/20 0.47
SCN1A P35498 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
LMNA P02545 3/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
P2RX7 Q99572 1/20 0.45
ITGB3 P05106 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200135 1.00 RAB9A (0.52) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL5062929 1.00 RAB9A (0.52) RAB9ANPC1HPGDALDH1A1POLB
Glycine SCHEMBL11339638 0.90 ITGB3 (0.45) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL3719428 0.85 TDP1 (0.50) RAB9ANPC1ALDH1A1POLBGAA
SCHEMBL411627 0.85 TDP1 (0.50) RAB9ANPC1ALDH1A1POLBGAA
SCHEMBL5968639 0.83 POLB (0.50) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL11194641 0.81 RAB9A (0.48) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL28246899 0.81 RAB9A (0.48) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL11194644 0.81 RAB9A (0.48) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL5323369 0.81 HPGD (0.49) RAB9ANPC1HPGDALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154960-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US claimed
CN-119823223-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2025-04-15 CN disclosed
CN-113396218-B Engineered transaminase polypeptides 科德克希思公司 2025-02-18 CN disclosed
CN-118829646-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2024-10-22 CN disclosed
CN-117362188-A Synthesis method of alpha-substituted deuterated amino acid ester 广州医科大学 2024-01-09 CN disclosed
EP-4136102-A1 LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE I2O Therapeutics, Inc. (US) 2023-02-22 EP disclosed
WO-2021212023-A1 LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE INTARCIA THERAPEUTICS, INC. (US) 2021-10-21 WO disclosed
US-20190201349-A1 CAPSULES AND PARTICLES AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2019-07-04 US disclosed
WO-2017072759-A1 CAPSULES AND PARTICLES AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-05-04 WO disclosed
CN-106573073-A FAP-activated therapeutics and uses related thereto 塔夫茨大学信托人 2017-04-19 CN disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-20020058622-A1 Sustained-release preparation IGARI YASUTAKA (JP) 2002-05-16 US disclosed
EP-1044214-A1 METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD Amersham Pharmacia Biotech AB (SE) 2000-10-18 EP disclosed
US-5994507-A CONTACTING AQUEOUS LIQUID CONTAINING ALBUMIN WITH A COMPOUND CONTAINING THE SCAFFOLD--C(=O)-NH-C(=C-)-C(=O)- AND HAVING BEEN PRE-CHECKED TO BIND TO THE ALBUMIN; FOR REMOVAL OF ALBUMIN FROM A SOLUTION OR FOR PURIFICATION OF ALBUMIN AMERSHAM PHARMACIA BIOTECH AB (SE) 1999-11-30 US disclosed
EP-0567470-B1 PSEUDOMONAS PEPTIDE COMPOSITION AND METHOD FOR PRODUCING THE SAME SYNTHETIC PEPTIDES INC (CA) 1999-09-15 EP disclosed
WO-1999033860-A1 METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD AMERSHAM PHARMACIA BIOTECH AB (SE) 1999-07-08 WO disclosed
US-5494672-A HAVING SEQUENCE CORRESPONDING TO C-TERMINAL PORTION OF THE PSEUDOMONAS AERUGINOSA PILIN PROTEIN; VACCINE S.P.I. SYNTHETIC PEPTIDES INCORPORATED (CA) 1996-02-27 US disclosed
EP-0567470-A1 PSEUDOMONAS PEPTIDE COMPOSITION AND METHOD FOR PRODUCING THE SAME S.P.I. SYNTHETIC PEPTIDES INCORPORATED (CA) 1993-11-03 EP disclosed
WO-1992012169-A1 PSEUDOMONAS PEPTIDE COMPOSITION AND METHOD FOR PRODUCING THE SAME S.P.I. SYNTHETIC PEPTIDES INCORPORATED (CA) 1992-07-23 WO disclosed
US-4435329-A ANTIHYPERTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1984-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190201349-A1 CAPSULES AND PARTICLES AND USES THEREOF ALG1, LPO, FUT5 RAB9A 1743/4885NPC1 2417/4885HPGD 2339/4885
US-20020058622-A1 Sustained-release preparation EDNRA, EDNRB, ORAI1 RAB9A 2849/4885NPC1 4562/4885HPGD 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.