Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140337 | 1.00 | KMT2A (0.41) | KMT2AHTTDYRK1AIDO1CHEK1 | |
| SCHEMBL5254693 | 0.80 | S1PR1 (0.36) | KMT2AHTTDYRK1AIDO1NPC1 | |
| SCHEMBL22140338 | 0.80 | MAPT (0.41) | AURKAMAP4K4AURKBUHRF1MAPT | |
| SCHEMBL24852675 | 0.78 | NOS3 (0.42) | PLAUUHRF1ALDH1A1KDM4ELMNA | |
| SCHEMBL30788039 | 0.78 | NOS3 (0.42) | PLAUUHRF1ALDH1A1KDM4ELMNA | |
| SCHEMBL2147947 | 0.78 | HTT (0.33) | KMT2AHTTNPC1PLAUALDH1A1 | |
| SCHEMBL30788049 | 0.77 | PGR (0.36) | HTTIDO1PLAUALDH1A1HSD17B10 | |
| SCHEMBL24852699 | 0.77 | PGR (0.36) | HTTIDO1PLAUALDH1A1HSD17B10 | |
| SCHEMBL25206015 | 0.77 | PLAU (0.43) | KMT2AHTTPLAUALDH1A1KDM4E | |
| SCHEMBL29818360 | 0.77 | PLAU (0.43) | KMT2AHTTPLAUALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580569-A | Heterocyclic aldehyde capture compounds and uses thereof | 奥尔德拉医疗公司 | 2024-02-20 | — | — | CN | disclosed |