Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788043 | 1.00 | KMT2A (0.41) | KMT2AHTTDYRK1AIDO1CHEK1 | |
| SCHEMBL5254693 | 0.80 | S1PR1 (0.36) | KMT2AHTTDYRK1AIDO1NPC1 | |
| SCHEMBL22140338 | 0.80 | MAPT (0.41) | AURKAMAP4K4AURKBUHRF1MAPT | |
| SCHEMBL24852675 | 0.78 | NOS3 (0.42) | PLAUUHRF1ALDH1A1KDM4ELMNA | |
| SCHEMBL30788039 | 0.78 | NOS3 (0.42) | PLAUUHRF1ALDH1A1KDM4ELMNA | |
| SCHEMBL2147947 | 0.78 | HTT (0.33) | KMT2AHTTNPC1PLAUALDH1A1 | |
| SCHEMBL30788049 | 0.77 | PGR (0.36) | HTTIDO1PLAUALDH1A1HSD17B10 | |
| SCHEMBL24852699 | 0.77 | PGR (0.36) | HTTIDO1PLAUALDH1A1HSD17B10 | |
| SCHEMBL25206015 | 0.77 | PLAU (0.43) | KMT2AHTTPLAUALDH1A1KDM4E | |
| SCHEMBL29818360 | 0.77 | PLAU (0.43) | KMT2AHTTPLAUALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580569-A | Heterocyclic aldehyde capture compounds and uses thereof | 奥尔德拉医疗公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20230365503-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365503-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-11753377-B2 | Crystal form of 2-methyl-2-propanol and amino-substituted aryl compound | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-09-12 | — | — | US | disclosed |
| US-11753377-B2 | Crystal form of 2-methyl-2-propanol and amino-substituted aryl compound | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-09-12 | — | — | US | disclosed |
| EP-4219451-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | Zhuhai United Laboratories Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| US-20230174489-A1 | CRYSTAL FORM OF 2-METHYL-2-PROPANOL AND AMINO-SUBSTITUTED ARYL COMPOUND | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-06-08 | — | — | US | disclosed |
| US-20230174489-A1 | CRYSTAL FORM OF 2-METHYL-2-PROPANOL AND AMINO-SUBSTITUTED ARYL COMPOUND | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-06-08 | — | — | US | disclosed |
| WO-2023278816-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| WO-2021254456-A1 | CRYSTAL FORM OF 2-METHYL-2-PROPANOL AND AMINO-SUBSTITUTED ARYL COMPOUND | 南京明德新药研发有限公司 | 2021-12-23 | — | — | WO | disclosed |
| EP-3901138-A1 | COMPOUND FOR USE IN RETINAL DISEASES | Medshine Discovery Inc. (CN) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020125659-A1 | COMPOUND FOR USE IN RETINAL DISEASES | 南京明德新药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174489-A1 | CRYSTAL FORM OF 2-METHYL-2-PROPANOL AND AMINO-SUBSTITUTED ARYL COMPOUND | CYP51A1, CYP4A11, CYP11B2 | KMT2A 1353/4885HTT 1386/4885DYRK1A 2584/4885 |
| US-20230365503-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | FARS2, CYP4F11, CYP4F8 | KMT2A 4316/4885HTT 1276/4885DYRK1A 2293/4885 |
| US-11753377-B2 | Crystal form of 2-methyl-2-propanol and amino-substituted aryl compound | CYP51A1, CYP4A11, CYP11B2 | KMT2A 1353/4885HTT 1386/4885DYRK1A 2584/4885 |
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ALDH1A2, ALDH1A3, NR2E3 | KMT2A 3459/4885HTT 1418/4885DYRK1A 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.