Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140341 | 0.88 | PGR (0.41) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL24131086 | 0.83 | PIK3CD (0.33) | MAPTCASP1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30788039 | 0.82 | NOS3 (0.42) | MAPTUHRF1 | |
| SCHEMBL24852675 | 0.82 | NOS3 (0.42) | MAPTUHRF1 | |
| SCHEMBL30788049 | 0.80 | PGR (0.36) | CYP11B2PGR | |
| SCHEMBL24852699 | 0.80 | PGR (0.36) | CYP11B2PGR | |
| SCHEMBL22140337 | 0.80 | KMT2A (0.41) | MAPTAURKAAURKBMAP4K4UHRF1 | |
| SCHEMBL30788043 | 0.80 | KMT2A (0.41) | MAPTAURKAAURKBMAP4K4UHRF1 | |
| SCHEMBL22140342 | 0.79 | PGR (0.38) | ALOX5APFEN1USP7PGR | |
| SCHEMBL22140350 | 0.79 | FEN1 (0.36) | PIK3CDALOX5APFEN1PIK3CBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| EP-3901138-A1 | COMPOUND FOR USE IN RETINAL DISEASES | Medshine Discovery Inc. (CN) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020125659-A1 | COMPOUND FOR USE IN RETINAL DISEASES | 南京明德新药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ALDH1A2, ALDH1A3, NR2E3 | MAPT 231/4885CASP1 4338/4885AURKA 4750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.