Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 4/20 | 0.50 |
| ▸ | GLP1R | P43220 | 10/20 | 0.49 |
| ▸ | SCTR | P47872 | 1/20 | 0.49 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31189098 | 0.88 | OPRD1 (0.48) | CALCRGLP1RSCTRIL23RC5AR1 | |
| SCHEMBL29367449 | 0.88 | GLP1R (0.58) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL29364498 | 0.88 | GLP1R (0.58) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL29367002 | 0.88 | GLP1R (0.58) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL29367867 | 0.88 | GLP1R (0.58) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL30668692 | 0.87 | CRHR1 (0.55) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL29499670 | 0.86 | CALCR (0.56) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL30084580 | 0.86 | OPRD1 (0.55) | GLP1RSCTRIL23ROPRD1 | |
| SCHEMBL30209624 | 0.86 | OPRM1 (0.54) | CALCRGLP1RSCTRCRHR1CRHR2 | |
| SCHEMBL30974489 | 0.85 | OPRD1 (0.49) | CALCRGLP1RSCTRCRHR1CRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3139955-B1 | FUSION PROTEINS FOR TREATING CANCER AND RELATED METHODS | HARVARD COLLEGE (US) | 2024-03-20 | — | — | EP | claimed |
| EP-3139955-B1 | FUSION PROTEINS FOR TREATING CANCER AND RELATED METHODS | HARVARD COLLEGE (US) | 2024-03-20 | — | — | EP | disclosed |