SCHEMBL30788458

SCHEMBL30788458

Fc1cccc(F)c1-c1ccccc1P(Cl)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
RPS6KA2 Q15349 1/20 0.31
ELANE P08246 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154086 0.81 CYP3A4 (0.36) TDP1
SCHEMBL29534836 0.81 CYP3A4 (0.36) TDP1
SCHEMBL8068834 0.79 CES2 (0.32) TDP1
SCHEMBL1768566 0.76 CYP3A4 (0.39) PDK2CA1CA2CA7CA9
SCHEMBL15530040 0.75 AR (0.32) ELANECYP1A2
SCHEMBL30788459 0.75 TOP1 (0.40) PDK2CA1CA2CA7CA9
SCHEMBL8033180 0.73 TDP1 (0.45) TDP1
SCHEMBL19009979 0.71 CYP3A4 (0.46) PDK2TDP1TTR
SCHEMBL2154282 0.67 ACHE (0.38)
SCHEMBL30426297 0.67 ACHE (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510686-A Method for preparing morphology-controllable ultra-high molecular weight polyethylene by in-situ polymerization 合肥中科科乐新材料有限责任公司 2024-02-06 CN disclosed