SCHEMBL2154086

SCHEMBL2154086

Fc1ccccc1P(Cl)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
NFE2L2 Q16236 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534836 1.00 CYP3A4 (0.36) CYP3A4TDP1ACHEALDH1A1ALOX15
SCHEMBL2154282 0.85 ACHE (0.38) ACHEALDH1A1ALOX15NFE2L2
SCHEMBL30426297 0.85 ACHE (0.38) ACHEALDH1A1ALOX15NFE2L2
SCHEMBL8068834 0.85 CES2 (0.32) CYP3A4TDP1NFE2L2
SCHEMBL8033180 0.83 TDP1 (0.45) CYP3A4TDP1ALDH1A1
SCHEMBL15530040 0.81 AR (0.32) CYP3A4ALDH1A1
SCHEMBL30788458 0.81 PDK2 (0.33) TDP1
SCHEMBL10797329 0.76 CYP3A4 (0.52) CYP3A4TDP1ACHENFE2L2
SCHEMBL29005861 0.76 CYP3A4 (0.52) CYP3A4TDP1ACHENFE2L2
SCHEMBL1041344 0.75 ACHE (0.38) ACHEALDH1A1ALOX15NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116328839-B Supported main catalyst for oligomerization of ethylene, catalyst composition for oligomerization of ethylene and application 中国石油化工股份有限公司 2025-02-28 CN disclosed
CN-116328837-B Ethylene oligomerization catalyst composition and application thereof 中国石油化工股份有限公司 2025-02-28 CN disclosed
CN-118847222-A Preparation method and application of PNP ligand synthetic solution for ethylene selective oligomerization chromium complex catalyst 大连理工大学 2024-10-29 CN disclosed
CN-116328836-B Porous organic polymer supported ethylene polymerization main catalyst, ethylene polymerization catalyst composition and application 中国石油化工股份有限公司 2024-09-20 CN disclosed
CN-116328839-A Supported main catalyst for oligomerization of ethylene, catalyst composition for oligomerization of ethylene and application 中国石油化工股份有限公司 2023-06-27 CN disclosed
CN-116328837-A Ethylene oligomerization catalyst composition and application thereof 中国石油化工股份有限公司 2023-06-27 CN disclosed
CN-116328838-A Metal-organic framework supported ethylene oligomerization catalyst composition and application thereof 中国石油化工股份有限公司 2023-06-27 CN disclosed
CN-116328836-A Porous organic polymer supported ethylene polymerization main catalyst, ethylene polymerization catalyst composition and application 中国石油化工股份有限公司 2023-06-27 CN disclosed
EP-2994445-B1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE SASOL TECH PTY LTD (ZA) 2023-05-24 EP disclosed
EP-2994445-B1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE SASOL TECH PTY LTD (ZA) 2023-05-24 EP disclosed
EP-2994445-A1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE Sasol Technology (Proprietary) Limited (ZA) 2016-03-16 EP disclosed
US-9283555-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2016-03-15 US disclosed
WO-2015094207-A1 PHOSPHINYL FORMAMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-06-25 WO disclosed
EP-2847150-A1 TETRAMERISATION OF ETHYLENE Sasol Technology (Proprietary) Limited (ZA) 2015-03-18 EP disclosed
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-08-07 US disclosed
US-8680003-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-03-25 US disclosed
WO-2013168106-A1 TETRAMERISATION OF ETHYLENE SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) 2013-11-14 WO disclosed
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-06 US disclosed
EP-2519532-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS Chevron Phillips Chemical Company LP (US) 2012-11-07 EP disclosed
WO-2011082192-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 CYP3A4 4787/4885TDP1 3539/4885ACHE 1107/4885
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 CYP3A4 4787/4885TDP1 3539/4885ACHE 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.