SCHEMBL2154282

SCHEMBL2154282

Fc1ccccc1P(Cl)c1ccccc1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
NFE2L2 Q16236 5/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
IDO1 P14902 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30426297 1.00 ACHE (0.38) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL2154086 0.85 CYP3A4 (0.36) ACHENFE2L2ALDH1A1ALOX15
SCHEMBL29534836 0.85 CYP3A4 (0.36) ACHENFE2L2ALDH1A1ALOX15
SCHEMBL1041344 0.83 ACHE (0.38) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL476837 0.77 ACHE (0.41) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL30700143 0.77 ACHE (0.41) ACHENFE2L2ALDH1A1ALOX15CES2
Hydrochloric Acid SCHEMBL11570761 0.74 ACHE (0.39) ACHENFE2L2ALDH1A1ALOX15CES2
Hydrochloric Acid SCHEMBL11570767 0.74 ACHE (0.39) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL15272385 0.72 ACHE (0.38) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL12620592 0.72 CES2 (0.39) ACHENFE2L2ALDH1A1ALOX15CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
EP-3907004-B1 HALOGEN-CONTAINING COMPOUND AND USE THEREOF, CATALYST COMPOSITION, AND ETHYLENE OLIGOMERIZATION, TRIMERIZATION AND TETRAMERIZATION METHODS CHINA PETROLEUM & CHEM CORP (CN) 2023-09-13 EP disclosed
CN-107548385-B Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-21 CN disclosed
CN-113896607-A Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
EP-3907004-A1 HALOGEN-CONTAINING COMPOUND AND USE THEREOF, CATALYST COMPOSITION, AND ETHYLENE OLIGOMERIZATION, TRIMERIZATION AND TETRAMERIZATION METHODS China Petroleum & Chemical Corporation (CN) 2021-11-10 EP disclosed
CN-107592863-B Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-09-10 CN disclosed
CN-107567355-B Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-06 US disclosed
US-10981156-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-20 US disclosed
US-10919031-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-16 US disclosed
WO-2015083053-A1 ETHYLENE OLIGOMERIZATION WITH MIXED LIGANDS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2015-06-11 WO disclosed
US-20150080629-A1 Tetramerisation of Ethylene SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) 2015-03-19 US disclosed
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-08-07 US disclosed
US-8680003-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-03-25 US disclosed
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-06 US disclosed
EP-2519532-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS Chevron Phillips Chemical Company LP (US) 2012-11-07 EP disclosed
WO-2011082192-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-07-07 WO disclosed
EP-2277623-A2 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2011-01-26 EP disclosed
EP-1448298-B1 POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS INVISTA TECH SARL (CH) 2010-09-22 EP disclosed
EP-1905511-A2 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2008-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ACHE 307/4885NFE2L2 256/4885ALDH1A1 4182/4885
US-10919031-B2 Process for oligomerization OXER1, NOD1, LIG1 ACHE 307/4885NFE2L2 256/4885ALDH1A1 4182/4885
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 ACHE 1107/4885NFE2L2 3797/4885ALDH1A1 4849/4885
US-10981156-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ACHE 110/4885NFE2L2 33/4885ALDH1A1 4013/4885
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 ACHE 1107/4885NFE2L2 3797/4885ALDH1A1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.