Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362820 | 0.84 | NLRP3 (0.44) | CTSKCTSSRENGSTP1GSTM2 | |
| SCHEMBL21946219 | 0.84 | NLRP3 (0.44) | CTSKCTSSRENGSTP1GSTM2 | |
| SCHEMBL29657321 | 0.84 | NLRP3 (0.44) | CTSKCTSSRENGSTP1GSTM2 | |
| SCHEMBL30788761 | 0.81 | CTSK (0.35) | CTSKCTSSRENGSTP1GSTM2 | |
| SCHEMBL3980233 | 0.77 | REN (0.36) | CTSKCTSSRENGSTP1GSTM2 | |
| SCHEMBL3980235 | 0.77 | REN (0.36) | CTSKCTSSRENGSTP1GSTM2 | |
| SCHEMBL6095308 | 0.76 | ITGB3 (0.47) | CTSKCTSSRENCYP3A4PPARG | |
| SCHEMBL21879135 | 0.76 | ITGB3 (0.47) | CTSKCTSSRENCYP3A4PPARG | |
| SCHEMBL20502152 | 0.76 | ITGB3 (0.47) | CTSKCTSSRENCYP3A4PPARG | |
| SCHEMBL30788866 | 0.75 | PPARA (0.53) | CTSKCTSSKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565228-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030960-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2024-02-08 | — | — | WO | disclosed |