Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16039402 | 1.00 | LRRK2 (0.36) | LRRK2DCLK1MAPK7BMPR1BPDGFRB | |
| SCHEMBL16039400 | 1.00 | LRRK2 (0.36) | LRRK2DCLK1MAPK7BMPR1BPDGFRB | |
| SCHEMBL16041807 | 0.86 | ADRA1D (0.33) | L3MBTL1ALDH1A1GAAADRA1DADRA1A | |
| SCHEMBL16088308 | 0.86 | ADRA1D (0.33) | L3MBTL1ALDH1A1GAAADRA1DADRA1A | |
| SCHEMBL21187331 | 0.83 | MEN1 (0.38) | LRRK2DCLK1MAPK7ALDH1A1MEN1 | |
| SCHEMBL30823285 | 0.83 | MEN1 (0.38) | LRRK2DCLK1MAPK7ALDH1A1MEN1 | |
| SCHEMBL21178069 | 0.83 | MEN1 (0.38) | LRRK2DCLK1MAPK7ALDH1A1MEN1 | |
| SCHEMBL30817826 | 0.82 | ALDH1A1 (0.40) | LRRK2DCLK1MAPK7SYKKIF11 | |
| SCHEMBL21187359 | 0.82 | ALDH1A1 (0.40) | LRRK2DCLK1MAPK7SYKKIF11 | |
| SCHEMBL28471532 | 0.82 | ALDH1A1 (0.40) | LRRK2DCLK1MAPK7SYKKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741955-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-02-23 | — | — | CN | disclosed |