Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 10/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21178069 | 1.00 | MEN1 (0.38) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL21187331 | 1.00 | MEN1 (0.38) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL21177900 | 0.86 | DCLK1 (0.39) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL30823307 | 0.86 | DCLK1 (0.39) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL21187336 | 0.86 | DCLK1 (0.39) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL30817826 | 0.85 | ALDH1A1 (0.40) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL21187359 | 0.85 | ALDH1A1 (0.40) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL28471532 | 0.85 | ALDH1A1 (0.40) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL30790695 | 0.83 | LRRK2 (0.36) | MEN1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL16039402 | 0.83 | LRRK2 (0.36) | MEN1ALDH1A1LMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757876-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-03-22 | — | — | CN | disclosed |