Sugi Predict

Sugi Predict / Compounds / SCHEMBL3079313

SCHEMBL3079313

SCHEMBL3079313

c1ccc(/N=N/c2ncccn2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 3/20 0.61
▸ MAOB P27338 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.60
▸ TRPA1 O75762 3/20 0.50
▸ KMT2A Q03164 7/20 0.46
▸ MEN1 O00255 6/20 0.46
▸ MAPT P10636 4/20 0.46
▸ NPC1 O15118 2/20 0.46
▸ PKM P14618 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ GLO1 Q04760 1/20 0.44
▸ MAPK1 P28482 5/20 0.41
▸ TDP1 Q9NUW8 4/20 0.41
▸ TSHR P16473 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ OPRK1 P41145 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3079314 1.00 MAOA (0.61) MAOAMAOBALDH1A1TRPA1KMT2A
SCHEMBL23628507 0.81 ALDH1A1 (0.55) MAOAMAOBALDH1A1TRPA1KMT2A
SCHEMBL23628506 0.81 ALDH1A1 (0.55) MAOAMAOBALDH1A1TRPA1KMT2A
SCHEMBL29919450 0.81 HDAC8 (0.39) MAOAMAOBALDH1A1KMT2AMEN1
SCHEMBL2469365 0.81 HDAC8 (0.39) MAOAMAOBALDH1A1KMT2AMEN1
SCHEMBL150449 0.79 MAOA (0.41) MAOAMAOBALDH1A1TRPA1KMT2A
Azobenzene SCHEMBL11878769 0.78 ALDH1A1 (1.00) MAOAMAOBALDH1A1TRPA1KMT2A
Azobenzene SCHEMBL32032 0.78 ALDH1A1 (1.00) MAOAMAOBALDH1A1TRPA1KMT2A
Azobenzene SCHEMBL11124477 0.78 ALDH1A1 (1.00) MAOAMAOBALDH1A1TRPA1KMT2A
SCHEMBL4011508 0.78 MEN1 (0.45) MAOAMAOBALDH1A1TRPA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2713736-B1 NOVEL IMMUNE SYSTEM MODULATORS JANUS BIOTHERAPEUTICS INC (US) 2023-08-02 — — EP disclosed
US-10117875-B2 Immune system modulators JANUS BIOTHERAPEUTICS, INC. (US) 2018-11-06 — — US disclosed
US-20170224699-A1 NOVEL IMMUNE SYSTEM MODULATORS Wilmer Cutler Pickering Hale and Dorr LLP 2017-08-10 — — US disclosed
US-9637489-B2 Immune system modulators JANUS BIOTHERAPEUTICS, INC. (US) 2017-05-02 — — US disclosed
US-9359361-B2 Immune system modulators JANUS BIOTHERAPEUTICS, INC. (US) 2016-06-07 — — US disclosed
US-9353115-B2 Immune system modulators JANUS BIOTHERAPEUTICS, INC. (US) 2016-05-31 — — US disclosed
EP-2713737-B1 NOVEL IMMUNE SYSTEM MODULATORS JANUS BIOTHERAPEUTICS INC (US) 2016-04-20 — — EP disclosed
US-20160074403-A1 NOVEL IMMUNE SYSTEM MODULATORS Wilmer Cutler Pickering Hale and Dorr LLP 2016-03-17 — — US disclosed
US-9126996-B2 Immune system modulators JANUS BIOTHERAPEUTICS, INC. (US) 2015-09-08 — — US disclosed
US-20140221646-A1 NOVEL IMMUNE SYSTEM MODULATORS JANUS BIOTHERAPEUTICS, INC. (US) 2014-08-07 — — US disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 — — WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 — — US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 — — US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 — — US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 — — US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 — — US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 — — US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221646-A1 NOVEL IMMUNE SYSTEM MODULATORS HLA-DRB1, CD47, MYD88 MAOA 4200/4885MAOB 3789/4885ALDH1A1 2143/4885
US-10117875-B2 Immune system modulators HLA-DRB1, CD47, MYD88 MAOA 2532/4885MAOB 2292/4885ALDH1A1 1649/4885
US-20160074403-A1 NOVEL IMMUNE SYSTEM MODULATORS HLA-DRB1, CD47, MYD88 MAOA 4200/4885MAOB 3789/4885ALDH1A1 2143/4885
US-20170224699-A1 NOVEL IMMUNE SYSTEM MODULATORS HLA-DRB1, CD47, MYD88 MAOA 4200/4885MAOB 3789/4885ALDH1A1 2143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.