SCHEMBL150449

SCHEMBL150449

[c]1ccc(N=Nc2ncccn2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
ALDH1A1 P00352 1/20 0.35
TRPA1 O75762 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GLO1 Q04760 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HIF1A Q16665 1/20 0.30
PHLPP2 Q6ZVD8 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3079314 0.79 MAOA (0.61) MAOAMAOBALDH1A1TRPA1MEN1
SCHEMBL3079313 0.79 MAOA (0.61) MAOAMAOBALDH1A1TRPA1MEN1
SCHEMBL2884844 0.78 ALDH1A1 (0.44) ALDH1A1MEN1KMT2A
SCHEMBL148832 0.78 MAOA (0.71) MAOAMAOBALDH1A1TRPA1KMT2A
SCHEMBL148831 0.78 MAOA (0.71) MAOAMAOBALDH1A1TRPA1KMT2A
SCHEMBL2469365 0.75 HDAC8 (0.39) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL29919450 0.75 HDAC8 (0.39) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL146201 0.75 CCNT1 (0.41) MAOAMAOBALDH1A1TRPA1MEN1
SCHEMBL146200 0.75 CCNT1 (0.41) MAOAMAOBALDH1A1TRPA1MEN1
SCHEMBL148167 0.74 ALDH1A1 (0.67) MAOAMAOBALDH1A1TRPA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344142-B2 perylenetetracarboxylic diimide core having side chains (groups or mesogens) attached to the core; to provide charge-transport materials having various volatilities, solubilities, crystallinity, and charge transport ability; organic light emitting diode; photovoltaic cells, light-emitting diodes GEORGIA TECH RESEARCH CORPORATION (US) 2013-01-01 US claimed
US-8039625-B2 Coronene charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-18 US claimed
US-20090044863-A1 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF NATIONAL SCIENCE FOUNDATION 2009-02-19 US claimed
US-20080223444-A1 Perylene Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof GEORGIA TECH RESEARCH CORPORATION 2008-09-18 US claimed
WO-2006093965-A2 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2006-09-08 WO claimed
WO-2005124453-A2 PERYLENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2005-12-29 WO claimed
CN-113330096-B Use of substituted or unsubstituted polycyclic aromatic compounds for high resolution microscopy 马克斯·普朗克索赔科学公司 2024-05-31 CN disclosed
US-11958796-B2 Hydrophilic and particularly water soluble DBOV-derivatives MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-04-16 US disclosed
CN-112839922-B Hydrophilic and in particular water-soluble DBOV derivatives 马克斯·普朗克索赔科学公司 2024-04-02 CN disclosed
EP-3830217-B1 USE OF A SUBSTITUTED OR UNSUBSTITUTED POLYCYCLIC AROMATIC HYDROCARBON COMPOUND FOR HIGH-RESOLUTION MICROSCOPY MAX PLANCK GESELLSCHAFT (DE) 2022-07-20 EP disclosed
US-20220009870-A1 HYDROPHILIC AND PARTICULARLY WATER SOLUBLE DBOV-DERIVATIVES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-01-13 US disclosed
US-20210388260-A1 USE OF A SUBSTITUTED OR UNSUBSTITUTED POLYCYCLIC AROMATIC HYDROCARBON COMPOUND FOR HIGH-RESOLUTION MICROSCOPY Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) 2021-12-16 US disclosed
CN-113330096-A Use of substituted or unsubstituted polycyclic aromatic hydrocarbon compounds for high resolution microscopy 马克斯·普朗克索赔科学公司 2021-08-31 CN disclosed
EP-0804508-B1 PROCESS FOR PRODUCING AND PURIFYING PERYLENE-3,4-DICARBOXYLIC ACID IMIDES BASF AG (DE) 1999-06-09 EP disclosed
EP-0804507-B1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AG (DE) 1999-04-28 EP disclosed
US-5808073-A CATALYTIC AMINATION OF THE CORRESPONDING PERYLENETETRACARBOXYLIC ACID OR ANHYDRIDE WITH PRIMARY AMINE IN TERTIARY AMINE SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
EP-0804508-A1 PROCESS FOR PRODUCING AND PURIFYING PERYLENE-3,4-DICARBOXYLIC ACID IMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-11-05 EP disclosed
EP-0804507-A1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-11-05 EP disclosed
WO-1996022332-A1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed
WO-1996022331-A1 PROCESS FOR PRODUCING AND PURIFYING PERYLENE-3,4-DICARBOXYLIC ACID IMIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009870-A1 HYDROPHILIC AND PARTICULARLY WATER SOLUBLE DBOV-DERIVATIVES NR1H4, HDGF, ABHD16A MAOA 3409/4885MAOB 3017/4885ALDH1A1 329/4885
US-20210388260-A1 USE OF A SUBSTITUTED OR UNSUBSTITUTED POLYCYCLIC AROMATIC HYDROCARBON COMPOUND FOR HIGH-RESOLUTION MICROSCOPY AHR, ARNT, SAMM50 MAOA 1264/4885MAOB 1148/4885ALDH1A1 3676/4885
US-11958796-B2 Hydrophilic and particularly water soluble DBOV-derivatives NR1H4, HDGF, ABHD16A MAOA 3409/4885MAOB 3017/4885ALDH1A1 329/4885
US-20080223444-A1 Perylene Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof SLC43A1, SLC3A2, SLC16A3 MAOA 2410/4885MAOB 2141/4885ALDH1A1 1563/4885
US-20090044863-A1 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF SLC18A3, CORO1C, SLC18A1 MAOA 1876/4885MAOB 2263/4885ALDH1A1 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.