Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797229 | 0.83 | RET (0.36) | BRD4CREBBPHTR2C | |
| SCHEMBL21804941 | 0.76 | ALOX5 (0.50) | L3MBTL1MGLL | |
| SCHEMBL21921407 | 0.76 | ALOX5 (0.50) | L3MBTL1MGLL | |
| SCHEMBL21804897 | 0.76 | ALOX5 (0.50) | L3MBTL1MGLL | |
| SCHEMBL30088143 | 0.76 | ALOX5 (0.50) | L3MBTL1MGLL | |
| SCHEMBL31663152 | 0.74 | GAA (0.44) | L3MBTL1 | |
| SCHEMBL2234874 | 0.74 | GAA (0.44) | L3MBTL1 | |
| SCHEMBL7608835 | 0.69 | MIF (0.42) | MIFBRD4CREBBPSLC5A1APP | |
| SCHEMBL19251341 | 0.67 | AGXT (0.71) | AGXTL3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL18933602 | 0.67 | AGXT (0.46) | MIFAGXTJAK1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |