Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 3/20 | 0.71 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.45 |
| ▸ | CHKA | P35790 | 2/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288609 | 0.85 | AGXT (0.73) | AGXTPRMT6HCRTR1HCRTR2 | |
| SCHEMBL13451177 | 0.85 | ADRB1 (0.62) | AGXTALDH1A1 | |
| SCHEMBL19240350 | 0.82 | AGXT (0.65) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL166575 | 0.80 | PRMT6 (0.65) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL18933602 | 0.79 | AGXT (0.46) | AGXTPRMT6CACNA2D1SLC6A2MAPT | |
| SCHEMBL4480384 | 0.79 | PRMT6 (0.68) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL22516758 | 0.78 | AGXT (0.46) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL195501 | 0.77 | AGXT (0.62) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10244433 | 0.77 | PRMT6 (0.61) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL19604155 | 0.77 | PRMT6 (0.60) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233352-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233352-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | HSPA2, HSP90AA1, HSP90AB1 | AGXT 3264/4885PRMT6 1134/4885L3MBTL3 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.