Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577931 | 0.83 | RAB9A (0.44) | RAB9ANPC1HPGDALDH1A1P2RX7 | |
| SCHEMBL20577930 | 0.83 | RAB9A (0.44) | RAB9ANPC1HPGDALDH1A1P2RX7 | |
| SCHEMBL27660386 | 0.82 | HPGD (0.47) | RAB9ANPC1HPGDPOLBALDH1A1 | |
| SCHEMBL16340022 | 0.81 | PYGL (0.53) | ITGB1ITGB3ITGAVITGA5RAB9A | |
| SCHEMBL8435071 | 0.81 | PYGL (0.53) | ITGB1ITGB3ITGAVITGA5RAB9A | |
| SCHEMBL28481705 | 0.81 | KCNQ2 (0.50) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11315276 | 0.81 | GAA (0.49) | RAB9ANPC1HPGDALDH1A1P2RX7 | |
| SCHEMBL10491009 | 0.80 | FABP4 (0.47) | RAB9ANPC1HPGDPOLBALDH1A1 | |
| SCHEMBL23077764 | 0.79 | CA12 (0.50) | RAB9ANPC1HPGDPOLBALDH1A1 | |
| SCHEMBL20780229 | 0.78 | MAPT (0.47) | RAB9ANPC1HPGDALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |