Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026512 | 0.85 | KMT2A (0.45) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL14930874 | 0.82 | ALDH1A1 (0.50) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL23747256 | 0.81 | MAPT (0.44) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL27360925 | 0.78 | MAPT (0.45) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL23774851 | 0.78 | MAPT (0.45) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL16722184 | 0.78 | HDAC3 (0.40) | MAPTHTTRAB9AHPGDALDH1A1 | |
| SCHEMBL16722187 | 0.78 | HDAC3 (0.40) | MAPTHTTRAB9AHPGDALDH1A1 | |
| SCHEMBL30797262 | 0.78 | ITGB1 (0.53) | MAPTNPC1RAB9AP2RX7HPGD | |
| SCHEMBL10412991 | 0.78 | ALOX12 (0.40) | MAPTALDH1A1L3MBTL1SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL10880000 | 0.77 | GABRA1 (0.47) | MAPTHPGDL3MBTL1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046364-A1 | INHIBITORS OF RSV REPLICATION AND APPLICATIONS THEREOF | EMORY UNIVERSITY (US) | 2019-03-07 | — | — | WO | disclosed |