SCHEMBL30798707

SCHEMBL30798707

CC(C)N1C(=O)C(=O)c2c1ccc(Br)c2F

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24718005 1.00 CA12 (0.32) CA12CA1CA2CA7CA9
SCHEMBL21848225 0.78 TTR (0.39) CA12CA1CA2CA7CA9
SCHEMBL24718014 0.73 TGM2 (0.36) PGR
SCHEMBL30404657 0.67 CUL4A (0.51) CA1CA2PGR
SCHEMBL22667213 0.67 CUL4A (0.51) CA1CA2PGR
SCHEMBL12913742 0.67 FAAH (0.42) CA1CA2
SCHEMBL17254677 0.63 PARK7 (0.45) CA1CA2CA7CA9
SCHEMBL29180980 0.62 CYP1B1 (0.52)
SCHEMBL24303350 0.61 USP2 (0.42) PGR
SCHEMBL21848246 0.61 TTR (0.39) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4323352-A1 MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE Arvinas Operations, Inc. (US) 2024-02-21 EP disclosed