Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ADH5 | P11766 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812903 | 0.82 | IDO1 (0.52) | CYP3A4MAPTCYP1A2CYP2D6MAPK1 | |
| SCHEMBL30764860 | 0.81 | CD38 (0.42) | CYP3A4CYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL7364258 | 0.76 | IDO1 (0.57) | CYP3A4MAPTCYP1A2CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL10438238 | 0.75 | IDO1 (0.56) | CYP3A4MAPTCYP1A2CYP2D6MAPK1 | |
| SCHEMBL15881145 | 0.75 | SIRT3 (0.49) | CYP3A4MAPTCYP1A2CYP2D6MAPK1 | |
| SCHEMBL31069770 | 0.75 | ADH5 (0.49) | CYP3A4MAPTLMNAIDO1BAZ2B | |
| SCHEMBL30151934 | 0.75 | ADH5 (0.49) | CYP3A4MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL811064 | 0.72 | DGAT1 (0.52) | CYP3A4MAPTMAPK1CYP2C19ALDH1A1 | |
| SCHEMBL29419925 | 0.72 | IDO1 (0.47) | CYP3A4MAPTCYP1A2CYP2D6MAPK1 | |
| SCHEMBL5319528 | 0.72 | IDO1 (0.47) | CYP3A4MAPTCYP1A2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | PHKA1, PHKA2, CSNK1A1 | CYP3A4 1286/4885MAPT 691/4885CYP1A2 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.