Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438610 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL23291099 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL926998 | 0.74 | LMNA (0.46) | ALDH1A1HSD17B10NAMPT | |
| Benzene SCHEMBL27557500 | 0.72 | LMNA (0.44) | ALDH1A1HSD17B10 | |
| Ethane SCHEMBL27342659 | 0.71 | LMNA (0.43) | ALDH1A1HSD17B10 | |
| Hydrazine SCHEMBL27534768 | 0.71 | LMNA (0.47) | ALDH1A1HSD17B10 | |
| SCHEMBL30799008 | 0.70 | PTPN1 (0.30) | — | |
| SCHEMBL27892934 | 0.70 | NAMPT (0.39) | ALDH1A1HSD17B10NAMPT | |
| SCHEMBL288903 | 0.69 | ALDH1A1 (0.45) | ALDH1A1HSD17B10NAMPT | |
| SCHEMBL288904 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HSD17B10NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116885-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | PHKA1, PHKA2, CSNK1A1 | ALDH1A1 1445/4885HSD17B10 1970/4885NAMPT 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.