Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799600 | 0.78 | KDM4E (0.46) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL30799621 | 0.74 | HSD17B10 (0.37) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL30242205 | 0.69 | LMNA (0.44) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL13895883 | 0.69 | LMNA (0.44) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL8236241 | 0.68 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EHSD17B10CASP1 | |
| SCHEMBL31042985 | 0.67 | ALDH1A1 (0.48) | ALDH1A1HTTKMT2AALOX15TRPM8 | |
| SCHEMBL1098273 | 0.67 | LIMK1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL30799595 | 0.67 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9433738 | 0.67 | MAPK1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL7848990 | 0.65 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683042-A | Fused tetracyclic compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-03-12 | — | — | CN | disclosed |