Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809560 | 0.69 | HTT (0.32) | HTTKMT2A | |
| SCHEMBL19360565 | 0.68 | DYRK1A (0.32) | HTTKMT2A | |
| SCHEMBL30483673 | 0.65 | HTT (0.32) | HTTKMT2A | |
| SCHEMBL20099798 | 0.64 | HTT (0.34) | HTTKMT2A | |
| SCHEMBL29640801 | 0.63 | TRPA1 (0.38) | — | |
| SCHEMBL9403398 | 0.61 | PRNP (0.46) | HTTKMT2A | |
| SCHEMBL5120809 | 0.61 | ADRA2A (0.47) | HTTKMT2A | |
| SCHEMBL17942177 | 0.59 | GRM5 (0.41) | HTTKMT2A | |
| SCHEMBL20595611 | 0.59 | DYRK1A (0.35) | HTTKMT2A | |
| SCHEMBL619585 | 0.59 | HTT (0.37) | HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853730-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |