Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119244 | 1.00 | TRPA1 (0.38) | TRPA1PNMTASIC3PARP10PARP11 | |
| SCHEMBL28118957 | 0.84 | TRPA1 (0.38) | TRPA1PNMTASIC3PARP10PARP11 | |
| SCHEMBL7070526 | 0.79 | TRPA1 (0.40) | TRPA1PNMTASIC3PARP10PARP11 | |
| SCHEMBL28218152 | 0.76 | — | — | |
| SCHEMBL7932158 | 0.76 | ADRA2A (0.34) | PARP10PARP11NOS3NOS1NOS2 | |
| SCHEMBL22780705 | 0.76 | — | — | |
| SCHEMBL6291964 | 0.76 | DRD2 (0.37) | — | |
| SCHEMBL10511659 | 0.76 | CYP11B2 (0.33) | PARP10CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL20896958 | 0.76 | HTR2A (0.38) | PNMTCYP19A1CYP11B1CYP11B2SRD5A1 | |
| SCHEMBL25940754 | 0.73 | TRPA1 (0.36) | TRPA1PNMTASIC3PARP10KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798161-A | Preparation method of plant growth regulating substance and multiple uses thereof | 贵州工业职业技术学院 | 2025-04-11 | — | — | CN | disclosed |
| CN-114085212-B | Isoindoline compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-05-02 | — | — | CN | disclosed |
| US-11401256-B2 | Dihydroquinolinones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| CN-109896998-B | 3, 4-dihydroisoquinoline sulfonamide compound and application thereof | 复旦大学 | 2022-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401256-B2 | Dihydroquinolinones for medical treatment | CRBN, RBX1, ADRM1 | TRPA1 4878/4885PNMT 3104/4885ASIC3 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.