Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30138402 | 0.85 | HTR1D (0.47) | MMP12P2RY14KMT2ANPC1RAB9A | |
| SCHEMBL30800028 | 0.82 | MMP12 (0.41) | MMP12P2RY14KMT2ANPC1RAB9A | |
| SCHEMBL11557197 | 0.82 | MMP12 (0.41) | MMP12P2RY14KMT2ANPC1RAB9A | |
| SCHEMBL4604722 | 0.82 | CA2 (0.44) | ATMGAAL3MBTL1MMP12P2RY14 | |
| SCHEMBL30138396 | 0.82 | HTR1A (0.48) | MMP12P2RY14KMT2ANPC1RAB9A | |
| SCHEMBL4606421 | 0.80 | MMP12 (0.47) | MMP12P2RY14KMT2ANPC1RAB9A | |
| SCHEMBL1875326 | 0.80 | MMP12 (0.46) | GAAMMP12KMT2ANPC1RAB9A | |
| SCHEMBL29687140 | 0.80 | PDGFRB (0.48) | GAAMMP12P2RY14KMT2ANPC1 | |
| SCHEMBL3997475 | 0.78 | RAB9A (0.45) | MMP12P2RY14KMT2ANPC1RAB9A | |
| SCHEMBL30799511 | 0.78 | RAB9A (0.45) | MMP12P2RY14KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512840-B1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | TSENG YUFENG JANE (US) | 2024-03-06 | — | — | EP | disclosed |