Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421173 | 0.94 | BACE1 (0.38) | BACE1OPRD1CTSDCASP3CASP7 | |
| SCHEMBL30799951 | 0.92 | PTPN1 (0.42) | BACE1OPRD1PTPN1BACE2 | |
| SCHEMBL30799953 | 0.92 | BACE1 (0.51) | BACE1OPRD1BACE2CTSD | |
| SCHEMBL30038651 | 0.91 | OPRD1 (0.43) | BACE1OPRD1BACE2CTSD | |
| SCHEMBL30799351 | 0.90 | LTA4H (0.40) | BACE1OPRD1PTPN1 | |
| SCHEMBL29511114 | 0.88 | BACE1 (0.41) | BACE1PTPN1CTSD | |
| SCHEMBL30607941 | 0.88 | BACE1 (0.41) | BACE1PTPN1CTSD | |
| SCHEMBL31514368 | 0.88 | BACE1 (0.49) | BACE1PTPN1BACE2CTSD | |
| SCHEMBL29421174 | 0.87 | BACE1 (0.37) | BACE1OPRD1CTSD | |
| SCHEMBL30567410 | 0.87 | BACE1 (0.38) | BACE1OPRD1CTSDCASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | BACE1 10/4885OPRD1 4412/4885PTPN1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.