Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SOD1 | P00441 | 1/20 | 0.45 |
| ▸ | DPYD | Q12882 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128495 | 1.00 | LMNA (0.50) | LMNASOD1DPYDMAPK1L3MBTL1 | |
| SCHEMBL30800038 | 0.86 | KDM4E (0.41) | LMNASOD1MAPK1L3MBTL1TSHR | |
| SCHEMBL29128210 | 0.86 | KDM4E (0.41) | LMNASOD1MAPK1L3MBTL1TSHR | |
| SCHEMBL30799972 | 0.83 | DAO (0.44) | DPYDMAPK1KDM4EALDH1A1 | |
| SCHEMBL29128397 | 0.83 | DAO (0.44) | DPYDMAPK1KDM4EALDH1A1 | |
| SCHEMBL30799876 | 0.78 | SOD1 (0.42) | LMNASOD1MAPK1L3MBTL1TSHR | |
| SCHEMBL29128291 | 0.78 | SOD1 (0.42) | LMNASOD1MAPK1L3MBTL1TSHR | |
| SCHEMBL30799922 | 0.78 | RAB9A (0.42) | LMNASOD1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30800062 | 0.77 | CYP1A2 (0.32) | LMNATSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29128313 | 0.77 | CYP1A2 (0.32) | LMNATSHRKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |