SCHEMBL30800730

SCHEMBL30800730

O=[PH](c1ccccc1)c1cc2ccccc2c(-c2cccc3ccccc23)c1[PH](=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.41
CES1 P23141 1/20 0.38
TYMP P19971 1/20 0.38
SOS1 Q07889 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ALPL P05186 1/20 0.35
GAA P10253 1/20 0.35
GSK3B P49841 1/20 0.35
ADK P55263 1/20 0.35
DNMT1 P26358 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MCL1 Q07820 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5440135 0.72 NR4A1 (0.41) KDM4EGAAALDH1A1HPGDCA1
SCHEMBL338172 0.70 CES1 (0.55) GPR84CES1TYMPSOS1KDM4E
Biphenyl SCHEMBL28230506 0.68 CES1 (0.49) GPR84CES1SOS1KDM4EMEN1
SCHEMBL7243627 0.67 CES1 (0.52) GPR84CES1TYMPSOS1KDM4E
SCHEMBL27263879 0.66 ALDH1A1 (0.53) TYMPKDM4EALPLGAAGSK3B
SCHEMBL29663473 0.66 GPR84 (0.53) GPR84CES1TYMPSOS1KDM4E
SCHEMBL19960410 0.65 ALDH1A1 (0.48) SOS1KDM4EMEN1KMT2AALDH1A1
SCHEMBL28209362 0.65 ALDH1A1 (0.46) GPR84CES1TYMPKDM4EALPL
SCHEMBL28620398 0.64 CES1 (0.49) GPR84CES1TYMPSOS1KDM4E
SCHEMBL2760735 0.64 LMNA (0.35) CES1KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447464-A Method for producing optically active compound 首日生物制药公司 2024-01-26 CN disclosed