SCHEMBL19960410

SCHEMBL19960410

O=[PH](c1ccccc1)c1ccc2c(ccc3ccccc32)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 4/20 0.48
CYP1B1 Q16678 2/20 0.48
HIF1A Q16665 2/20 0.48
HPRT1 P00492 4/20 0.46
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 4/20 0.43
MAPT P10636 1/20 0.43
CYP1A2 P05177 6/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
SOS1 Q07889 1/20 0.40
CYP1A1 P04798 1/20 0.40
PAX8 Q06710 1/20 0.39
CYP2C19 P33261 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13240565 0.84 CES2 (0.39) ALDH1A1HSD17B10CYP2A6TDP1HPGD
SCHEMBL29613122 0.78 CES2 (0.43) ALDH1A1HSD17B10CYP2A6TDP1CYP1A2
SCHEMBL1304753 0.78 CES2 (0.43) ALDH1A1HSD17B10CYP2A6TDP1CYP1A2
SCHEMBL28347371 0.76 CYP1A2 (0.50) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL821938 0.74 ALDH1A1 (0.33) ALDH1A1CYP2A6TSHRTDP1MAPT
SCHEMBL28335942 0.74 CA4 (0.35) ALDH1A1CYP2A6TSHRTDP1MAPT
SCHEMBL3180469 0.73 ATM (0.33) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL13583073 0.72 ALDH1A1 (0.35) ALDH1A1CYP2A6TSHRTDP1MAPT
SCHEMBL1667 0.72 ALDH1A1 (0.35) ALDH1A1CYP2A6TSHRTDP1MAPT
SCHEMBL19376809 0.72 ALOX5 (0.55) ALDH1A1HSD17B10CYP1B1HIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10700289-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-06-30 US disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 ALDH1A1 750/4885HSD17B10 2882/4885CYP1B1 358/4885
US-10700289-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 ALDH1A1 750/4885HSD17B10 2882/4885CYP1B1 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.