Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969745 | 0.86 | ALDH1A1 (0.39) | — | |
| SCHEMBL22443333 | 0.80 | RIPK1 (0.32) | FKBP1A | |
| SCHEMBL22443334 | 0.80 | RIPK1 (0.32) | FKBP1A | |
| SCHEMBL30742994 | 0.80 | LMNA (0.33) | FKBP1A | |
| SCHEMBL25282754 | 0.77 | PPM1D (0.34) | FKBP1A | |
| SCHEMBL17674517 | 0.77 | PPM1D (0.34) | FKBP1A | |
| SCHEMBL4214203 | 0.76 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL2957842 | 0.76 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL4972513 | 0.76 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL26621489 | 0.76 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010314-B1 | HETEROARYL PYRROLIDINE AND PIPERIDINE OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-02-28 | — | — | EP | disclosed |