Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6191319 | 1.00 | FDPS (0.52) | FDPSALDH1A1RECQLNAPRTCYP1A2 | |
| SCHEMBL10657868 | 0.87 | ALDH1A1 (0.67) | FDPSALDH1A1RECQLNAPRTMMP8 | |
| SCHEMBL10657875 | 0.87 | ALDH1A1 (0.67) | FDPSALDH1A1RECQLNAPRTMMP8 | |
| SCHEMBL10657871 | 0.87 | ALDH1A1 (0.67) | FDPSALDH1A1RECQLNAPRTMMP8 | |
| SCHEMBL28168069 | 0.82 | ALDH1A1 (0.67) | ALDH1A1RECQLCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5570727 | 0.82 | ALDH1A1 (0.71) | FDPSALDH1A1RECQLCYP1A2CYP3A4 | |
| SCHEMBL30476792 | 0.82 | ALDH1A1 (0.71) | FDPSALDH1A1RECQLCYP1A2CYP3A4 | |
| SCHEMBL9503704 | 0.82 | KMT2A (0.64) | FDPSALDH1A1RECQLNAPRTCYP1A2 | |
| SCHEMBL4065071 | 0.81 | ALDH1A1 (0.50) | FDPSALDH1A1RECQLCYP1A2CYP3A4 | |
| SCHEMBL7861665 | 0.76 | FDPS (0.59) | FDPSALDH1A1NAPRTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |