Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | FDPS | P14324 | 3/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528161 | 0.85 | ALDH1A1 (0.48) | KMT2APKMCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6191319 | 0.82 | FDPS (0.52) | FDPSNAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30801043 | 0.82 | FDPS (0.52) | FDPSNAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10594354 | 0.78 | KMT2A (1.00) | KMT2APKMCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8421523 | 0.78 | KMT2A (0.39) | KMT2APKMRECQLLMNAHTT | |
| SCHEMBL10657871 | 0.74 | ALDH1A1 (0.67) | KMT2APKMFDPSNAPRTL3MBTL1 | |
| SCHEMBL8954953 | 0.74 | FOLH1 (0.43) | KMT2APKMLMNA | |
| SCHEMBL10657868 | 0.74 | ALDH1A1 (0.67) | KMT2APKMFDPSNAPRTL3MBTL1 | |
| SCHEMBL10657875 | 0.74 | ALDH1A1 (0.67) | KMT2APKMFDPSNAPRTL3MBTL1 | |
| SCHEMBL8426514 | 0.73 | ALDH1A1 (0.46) | KMT2ACYP1A2CYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299402-B1 | LHRH ANTAGONISTS, THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF | ASTA Medica Aktiengesellschaft (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0299402-A2 | LHRH antagonists, their manufacture and pharmaceutical compositions thereof | ASTA Medica Aktiengesellschaft (DE) | 1989-01-18 | — | — | EP | disclosed |