Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801716 | 0.91 | CCR1 (0.51) | CCR1CTSLCTSSCTSKCTSB | |
| SCHEMBL30801737 | 0.82 | CCR1 (0.48) | CCR1CTSLCTSSCTSKCTSB | |
| SCHEMBL30801747 | 0.76 | GRIN2B (0.48) | — | |
| SCHEMBL30801693 | 0.74 | GRIN2B (0.47) | DPP4DPP7PREP | |
| SCHEMBL19853771 | 0.74 | GRIN2B (0.41) | DPP4KCNH2DPP7ALDH1A1 | |
| SCHEMBL17281441 | 0.74 | CCR1 (0.50) | CCR1CTSLCTSSCTSKCTSB | |
| SCHEMBL30801704 | 0.73 | CCR1 (0.55) | CCR1CTSLCTSSCTSKCTSB | |
| SCHEMBL13502399 | 0.72 | CTSL (0.58) | CCR1CTSLCTSSCTSKCTSB | |
| SCHEMBL21034523 | 0.72 | OPRM1 (0.42) | DPP4 | |
| SCHEMBL19853726 | 0.72 | OPRM1 (0.42) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |