Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801737 | 0.89 | CCR1 (0.48) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL30801720 | 0.84 | TGM2 (0.49) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL15937145 | 0.81 | CTSL (0.47) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL30801716 | 0.80 | CCR1 (0.51) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL17352410 | 0.79 | CTSL (0.46) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL13502399 | 0.76 | CTSL (0.58) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL28646428 | 0.76 | P2RX7 (0.56) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL28646426 | 0.76 | P2RX7 (0.56) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL9096307 | 0.74 | CTSB (0.71) | CCR1CTSLCTSSCTSBCTSK | |
| SCHEMBL9096301 | 0.74 | CTSB (0.71) | CCR1CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |