Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937145 | 0.88 | CTSL (0.47) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL29648912 | 0.87 | CTSK (0.42) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL26089693 | 0.86 | CCR1 (0.42) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL26089697 | 0.86 | CCR1 (0.42) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL21051196 | 0.82 | P2RX7 (0.43) | CTSBCTSKCTSLCCR1MEN1 | |
| SCHEMBL21051198 | 0.82 | P2RX7 (0.43) | CTSBCTSKCTSLCCR1MEN1 | |
| SCHEMBL21051197 | 0.82 | P2RX7 (0.43) | CTSBCTSKCTSLCCR1MEN1 | |
| SCHEMBL19839889 | 0.79 | CCKBR (0.39) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL19839886 | 0.79 | CCKBR (0.39) | CTSBCTSKCTSLCAPN1CCR1 | |
| SCHEMBL17282838 | 0.77 | PREP (0.49) | CTSBCTSKCTSLCAPN1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |