Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801754 | 0.85 | CREBBP (0.35) | METAP2GPR119HDAC8HDAC6HDAC1 | |
| SCHEMBL23574118 | 0.83 | USP30 (0.35) | ROCK2 | |
| SCHEMBL30986844 | 0.83 | USP30 (0.35) | ROCK2 | |
| SCHEMBL23574125 | 0.83 | USP30 (0.35) | ROCK2 | |
| SCHEMBL30801736 | 0.81 | USP30 (0.39) | METAP2GPR119TDO2ROCK2 | |
| SCHEMBL30801817 | 0.80 | MAPT (0.39) | GPR119HDAC8HDAC6HDAC1TDO2 | |
| SCHEMBL30801833 | 0.78 | F10 (0.40) | GPR119HDAC8HDAC6HDAC1ROCK2 | |
| SCHEMBL30801875 | 0.76 | TYRO3 (0.37) | ROCK2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30801809 | 0.76 | METAP2 (0.39) | METAP2TDO2ROCK2 | |
| SCHEMBL30801755 | 0.75 | TYRO3 (0.34) | ROCK2CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |