Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801888 | 0.87 | ROCK2 (0.38) | METAP2USP30OTUD7BCREBBPROCK2 | |
| SCHEMBL30801754 | 0.85 | CREBBP (0.35) | METAP2TDO2CREBBPCNR2ROCK2 | |
| SCHEMBL30801838 | 0.85 | OTUD7B (0.35) | METAP2OTUD7BCREBBPCNR2ROCK2 | |
| SCHEMBL30801736 | 0.85 | USP30 (0.39) | METAP2USP30TDO2ROCK2BRD4 | |
| SCHEMBL23574031 | 0.83 | USP30 (0.49) | METAP2ABL1USP30OTUD7BCREBBP | |
| SCHEMBL23574029 | 0.83 | USP30 (0.49) | METAP2ABL1USP30OTUD7BCREBBP | |
| SCHEMBL30986836 | 0.83 | USP30 (0.49) | METAP2ABL1USP30OTUD7BCREBBP | |
| SCHEMBL30801833 | 0.80 | F10 (0.40) | ROCK2CHRNA7KCNH2 | |
| SCHEMBL30801817 | 0.78 | MAPT (0.39) | USP30TDO2ROCK2KCNH2 | |
| SCHEMBL30801740 | 0.76 | METAP2 (0.33) | METAP2TDO2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |