Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801809 | 0.85 | METAP2 (0.39) | USP30TDO2BRD4ROCK2METAP2 | |
| SCHEMBL23574032 | 0.83 | USP30 (0.49) | USP30NUDT1TNIKCSNK1DMAPK11 | |
| SCHEMBL23574036 | 0.83 | USP30 (0.49) | USP30NUDT1TNIKCSNK1DMAPK11 | |
| SCHEMBL30801754 | 0.81 | CREBBP (0.35) | TDO2ROCK2METAP2GPR119 | |
| SCHEMBL30801740 | 0.81 | METAP2 (0.33) | TDO2ROCK2METAP2GPR119 | |
| SCHEMBL30801817 | 0.80 | MAPT (0.39) | USP30TDO2ROCK2GPR119ATR | |
| SCHEMBL30801833 | 0.78 | F10 (0.40) | ROCK2GPR119ATR | |
| SCHEMBL30801838 | 0.72 | OTUD7B (0.35) | BRD4ROCK2METAP2CHEK1ATR | |
| SCHEMBL30801888 | 0.72 | ROCK2 (0.38) | USP30BRD4ROCK2METAP2PRKCQ | |
| SCHEMBL30801875 | 0.70 | TYRO3 (0.37) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |