Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801755 | 0.89 | TYRO3 (0.34) | CREBBPTYRO3ROCK2MET | |
| SCHEMBL30801875 | 0.88 | TYRO3 (0.37) | TYRO3ROCK2MET | |
| SCHEMBL30801871 | 0.86 | TYRO3 (0.34) | TYRO3CNR2ROCK2MET | |
| SCHEMBL30801809 | 0.85 | METAP2 (0.39) | CREBBPCNR2ROCK2METAP2TDO2 | |
| SCHEMBL30801740 | 0.85 | METAP2 (0.33) | ROCK2HDAC8HDAC6METAP2HDAC1 | |
| SCHEMBL23573936 | 0.83 | CREBBP (0.36) | CREBBPCNR2ROCK2 | |
| SCHEMBL30986845 | 0.83 | CREBBP (0.36) | CREBBPCNR2ROCK2 | |
| SCHEMBL23573932 | 0.83 | CREBBP (0.36) | CREBBPCNR2ROCK2 | |
| SCHEMBL30801736 | 0.81 | USP30 (0.39) | ROCK2METAP2TDO2GPR119 | |
| SCHEMBL30801833 | 0.80 | F10 (0.40) | ROCK2HDAC8HDAC6HDAC1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |