Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801744 | 0.89 | NPC1 (0.38) | NPC1RAB9AHTR2CMEN1KMT2A | |
| SCHEMBL30801805 | 0.89 | CRHBP (0.43) | DRD2HTR2CNOTUM | |
| SCHEMBL30801830 | 0.89 | CRHBP (0.43) | DRD2HTR2CNOTUM | |
| SCHEMBL30801748 | 0.81 | USP30 (0.39) | DRD2DRD3HTR2C | |
| SCHEMBL30801848 | 0.81 | USP30 (0.39) | DRD2DRD3HTR2C | |
| SCHEMBL30801850 | 0.80 | USP30 (0.39) | NPC1RAB9AHTR2CMEN1KMT2A | |
| SCHEMBL30801750 | 0.80 | PARP1 (0.39) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL23574050 | 0.79 | USP30 (0.46) | DRD2DRD4DRD3 | |
| SCHEMBL23574048 | 0.79 | USP30 (0.46) | DRD2DRD4DRD3 | |
| SCHEMBL30801758 | 0.79 | DPP4 (0.39) | NPC1RAB9AHTR2CIDH1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |