Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3605372 | 0.88 | HTR2C (0.48) | DRD2HTR2AHTR2CHTR2BCYP2C19 | |
| SCHEMBL30801775 | 0.85 | HTR1A (0.49) | HTR2AHTR2CHTR2BCYP2C19HTR1A | |
| SCHEMBL30801829 | 0.84 | SLC6A2 (0.51) | HTR2AHTR2CHTR2BCYP2C19HTR1A | |
| SCHEMBL30801864 | 0.83 | ALDH1A1 (0.51) | DRD2HTR2AHTR2CHTR2BHTR3E | |
| SCHEMBL30801713 | 0.82 | HTR2A (0.45) | HTR2AHTR2CHTR2BSLC6A4HTT | |
| SCHEMBL30801777 | 0.81 | HTR2C (0.38) | DRD2HTR2AHTR2CHTR2BCYP2C19 | |
| SCHEMBL30801874 | 0.81 | HTR2C (0.38) | DRD2HTR2AHTR2CHTR2BCYP2C19 | |
| SCHEMBL30801834 | 0.78 | HTR2C (0.47) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL30801816 | 0.78 | TP53 (0.41) | DRD2HTR2AHTR2CHTR2BTP53 | |
| SCHEMBL30801868 | 0.78 | DPP4 (0.42) | DRD2HTR2AHTR2CHTR2BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |