Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NMT2 | O60551 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097220 | 0.87 | MAOB (0.53) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL3261638 | 0.84 | TSHR (0.52) | L3MBTL1KMT2AMEN1TSHRJAK2 | |
| SCHEMBL7512109 | 0.81 | TSHR (0.47) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL12970520 | 0.81 | PDE10A (0.47) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL6228468 | 0.79 | TSHR (0.45) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL5778710 | 0.79 | SMN1; SMN2 (0.52) | L3MBTL1RAB9ATSHRNPSR1KDM4E | |
| SCHEMBL24906443 | 0.78 | RAB9A (0.53) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL7512103 | 0.78 | SMN1; SMN2 (0.62) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL4700131 | 0.78 | L3MBTL1 (0.51) | L3MBTL1KMT2AMEN1HSP90AA1RAB9A | |
| SCHEMBL4854023 | 0.78 | TSHR (0.46) | L3MBTL1KMT2AMEN1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365632-B | Aminopyrimidine compounds | 卡都瑞恩医药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-3856188-B1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS INC (US) | 2023-06-21 | — | — | EP | disclosed |
| US-20220112184-A1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS, LLC | 2022-04-14 | — | — | US | disclosed |
| US-11130752-B2 | Aminopyrimidine compound | CARDURION PHARMACEUTICALS, LLC (US) | 2021-09-28 | — | — | US | disclosed |
| CN-113365632-A | Aminopyrimidine compounds | 卡都瑞恩医药有限责任公司 | 2021-09-07 | — | — | CN | disclosed |
| EP-3856188-A1 | AMINOPYRIMIDINE COMPOUND | Cardurion Pharmaceuticals, LLC (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020068854-A1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS, LLC (US) | 2020-04-02 | — | — | WO | disclosed |
| US-20200095240-A1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS, LLC | 2020-03-26 | — | — | US | disclosed |
| EP-2840080-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-9023882-B2 | 5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-20120289506-A1 | 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20120289506-A1 | 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20120289506-A1 | 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-8227500-B2 | 5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-8227500-B2 | 5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-8227500-B2 | 5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20100227864-A1 | 5-MEMBERED HETEROCYCLIC DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-09 | — | — | US | disclosed |
| US-20100227864-A1 | 5-MEMBERED HETEROCYCLIC DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-09 | — | — | US | disclosed |
| US-20100227864-A1 | 5-MEMBERED HETEROCYCLIC DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-09 | — | — | US | disclosed |
| EP-2133331-A1 | 5-MEMBERED HETEROCYCLIC DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130752-B2 | Aminopyrimidine compound | CALM1, CAMK4, CAMK2B | L3MBTL1 2123/4885KMT2A 1599/4885MEN1 4267/4885 |
| US-20100227864-A1 | 5-MEMBERED HETEROCYCLIC DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | XDH, DAO, CBR1 | L3MBTL1 499/4885KMT2A 1484/4885MEN1 3974/4885 |
| US-20200095240-A1 | AMINOPYRIMIDINE COMPOUND | CALM1, CAMK4, CAMK2B | L3MBTL1 2123/4885KMT2A 1599/4885MEN1 4267/4885 |
| US-20120289506-A1 | 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | XDH, DAO, DDO | L3MBTL1 879/4885KMT2A 1715/4885MEN1 4123/4885 |
| US-20220112184-A1 | AMINOPYRIMIDINE COMPOUND | CALM1, CAMK4, CAMK2B | L3MBTL1 2123/4885KMT2A 1599/4885MEN1 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.