Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801829 | 0.90 | SLC6A2 (0.51) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL30801844 | 0.82 | DRD2 (0.49) | HTR2AHTR2CHTR2BSLC6A4ALDH1A1 | |
| SCHEMBL30801834 | 0.81 | HTR2C (0.47) | HTR2AHTR2CHTR2BALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3609575 | 0.79 | SLC6A2 (0.49) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL23573996 | 0.76 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL23573997 | 0.76 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL30801775 | 0.75 | HTR1A (0.49) | HTR2AHTR2CHTR2BALDH1A1HIF1A | |
| Hydrochloric Acid SCHEMBL3604903 | 0.74 | ADRB1 (0.35) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL30801864 | 0.73 | ALDH1A1 (0.51) | HTR2AHTR2CHTR2BALDH1A1MAPT | |
| SCHEMBL30801822 | 0.72 | LTA4H (0.49) | HTR2AHTR2CHTR2BALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |