Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801844 | 0.85 | DRD2 (0.49) | HTR1AHTR7ALDH1A1TP53CYP1A2 | |
| SCHEMBL30801761 | 0.81 | COMT (0.38) | HTR1AHTR7TAAR1HTR2AHTR2C | |
| SCHEMBL30801864 | 0.81 | ALDH1A1 (0.51) | HTR7ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL30801822 | 0.78 | LTA4H (0.49) | ALDH1A1TAAR1MGLLHTR2AHTR2C | |
| SCHEMBL30801833 | 0.77 | F10 (0.40) | TAAR1MGLLHTR2AHTR2CHTR2B | |
| SCHEMBL30801829 | 0.77 | SLC6A2 (0.51) | HTR1AALDH1A1CYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL3609828 | 0.76 | SLC6A2 (0.39) | HTR1AHTR7TAAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL3609734 | 0.76 | TAAR1 (0.42) | ALDH1A1TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL23574003 | 0.76 | USP30 (0.46) | ALDH1A1MGLLFAAHHSP90AA1PKM | |
| SCHEMBL30801882 | 0.76 | USP30 (0.46) | ALDH1A1MGLLFAAHHSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |